There are other methods to categorize symptoms of depression see [3] but we note that our categorization took into consideration symptoms across 8 common disorders. However, even here some questionnaires were more dominantly focused on one or the other category. The other categories were even more heterogeneously distributed across the questionnaires — in many cases represented only in some and not others. What does this tell us about depression and what it is?
Figure 1: The percentage breakdown of symptoms being assessed across different questionnaires. If we then look more generally at whether a question asks about the way someone feels emotion , the way someone thinks cognitive , the way someone acts behavior , a physical symptom physical , or about a particular trigger trigger or consequence consequence of a symptom this gives us a further impression, shown in figure 2, of how depression as an overall disorder is being assessed.
Figure 2: The percentage breakdown of symptom types being assessed across different questionnaires. However, again we find that the bias e. This raises the question: although we typically think of depression as an internalizing disorder, is it right that these depression questionnaires although see [4] hardly ask about the actions or behavior of the patient?
Where does that leave the understanding of depression? In a bit of a mess, really. Given the heterogeneity of depression itself, it is perhaps not that surprising that different questionnaires are asking about different symptoms. However, since the underlying physiology of depression is yet unknown, a standardized symptom set would be essential for research that is seeking links to depression and its many manifestations.
What it means is that your particular choice of depression questionnaire could make a big difference to the results you find, especially when you consider that the patients with depression in your study will also vary in the particular array of symptoms that they present.
With so much variability, it is perhaps not surprising that researchers have struggled for decades to make any sizeable progress in treating depression. Despite these concerns, it is still relatively rare for researchers to justify the use of one assessment questionnaire over another in their publication, or to give more weight to the specific symptoms of the patient, rather than the disorder label although that is changing to some degree with initiatives like RDoC.
However, careful consideration of which questionnaire you choose is merited, especially as the research community moves away from seeing depression as a one-size fits all label for a loosely connected cluster of symptoms.
Front Hum Neurosci. The 52 symptoms of major depression: Lack of content overlap among seven common depression scales. Journal Of Affective Disorders , , As a Board Member at Sapien Labs Rob brings a perspective on team building and strategies to integrate research into consumer and healthcare products. Rob is a senior executive at Avalere Health with deep healthcare relationships and a broad understanding of the behavioral health space including expert understanding of the models used by large companies and payers to address behavioral health.
He has advised large private equity investors in the diligence and purchase of companies delivering substance abuse treatment; outpatient psychiatry, autism services and running inpatient care for eating and other disorders. As human beings we all struggle through our lifetimes to understand the elements that shape our mental trajectories and drive our emotions and decisions.
Being part of Sapien Labs is, in this sense, a personal journey that has brought, and continues to bring, new perspectives to this understanding.
What also captures my imagination though is the possibility of turning these insights and ideas into something real that can integrate tangibly into the world at scale to help millions of people better navigate their mental challenges. What are the mechanisms to get us there faster? What are models that can work?
Solving these challenges in the context of a smart, committed team is what I find most interesting and rewarding. Uttara brings a global public health perspective to Sapien Labs, particularly with respect to practical ways to deliver research insights in cognitive and mental health as effective public health communication. She is also the founder of Nalamdana, a non-profit for health communication in India, which she founded in as an echoing green fellow.
Understanding these better will go a long way in strengthening caregiving and education strategies in early childhood, childhood and adolescence. Grig works with Sapien Labs as a core part of its team on crafting its communication and outreach and enabling strategic partnerships across relevant stakeholders.
Grigis a filmmaker, PR and digital media strategist with a particular interest in communication that can make the world a better place. He also co-founded Asteroid Day with astrophysicist and Queen guitarist Brian May, playing a key role in bringing together stakeholders and outreach to garner broad global awareness. He is also an ardent activist and has organized numerous advocacy events. In he walked from Paris to Berlin, making over one Million steps, to raise awareness about 1, unaccompanied refugee children in Greece that ended in the German government agreeing to find a solution for the children.
Bringing together stakeholders to shed greater light on mental health issues through science and stories at Sapien Labs is challenging yet so fulfilling. Callyn joined Sapien Labs in and manages marketing and events, including coordination of all virtual symposia which she has helped design and launch. She also supports the marketing outreach of the WorkforceMHQ product.
She has over 10 years of experience working in marketing and events and previously managed large trade shows and hosted events, including all aspects of event strategy, planning, execution, marketing and communication. Callyn has an M. It is an honor to be part of an organization that has amazing ambitions — improving mental health on a global scale.
Maya brings to Sapien Labs a perspective on ways to integrate research insights into curriculum and policy in education for better learning and wellbeing. She has previously taught in a wide range of high schools including public school in New Hampshire and inner-city Baltimore as part of Teach for America, and in private schools in New York City, Boston and most recently at UWC Singapore. She now serves on the Board of the Kodaikanal International School.
As an educator, I am fascinated by the differences in how people learn and navigate the world and how this is influenced by culture, methods of teaching and life experiences. Finding ways to enable better adolescent mental health and cognitive health in low-income communities for greater school success are also both particularly important challenges that I am excited to contribute to.
Jennifer came to Sapien Labs out of a curiosity for the workings of the human mind and a desire to blend academic research with real world impact. At Sapien Labs she has spearheaded the development of the MHQ and the global roll-out of the Mental Health Million Project and continues to lead data exploration and the development of novel tools.
Her previous research has spanned multiple subfields of the brain including cognitive neuroscience, olfaction science, and mental health and wellbeing where she has worked on the relationship between attention and memory, scene reconstruction in memory and imagination using fMRI, and the translation of olfaction induced insights using EEG and measures of emotional, physical and mental wellbeing into product design.
Prior to Sapien Labs she was Head of Neuroscience Research at Givaudan and brings a broad perspective across academic, commercial and not-for profit organizations. She has a Ph. Hons in Neuroscience from the University of Edinburgh. I am also excited to be able to bring together my background across neuroscience and cognitive neuroscience and my experience in translating fundamental science into technologies in the commercial sector to build something useful for the field of mental health care.
He is certified across multiple digital marketing platforms. Joe has a B. It is highly rewarding to be working with an organization that is driving real change in our understanding of mental health and wellbeing. The Sapien Labs mission is fundamental to our collective future, and as a marketer, being able to contribute even a little is an incredible opportunity. My goal at Sapien Labs is to apply the techniques of reaching the right people with the right message, to an audience that is as large and diverse as the entire planet.
Narayan has a longstanding interest in complex systems, statistical signal processing, computational modeling and nonlinear time series analysis, with applications to functional neuroimaging data EEG, MEG , including brain connectivity estimation. He has previously worked on quantifying structural properties of EEG data based on complex networks and nonlinear dynamics, with applications to derive EEG-based biomarkers for epilepsy.
Prior to his scientific study he worked as a software engineer at MindTree, India on end-to-end SAP implementations for businesses. His other interests include pedagogical tools for teachers in higher education.
Narayan has an M. And neuroscientists are focusing on the role of the autonomic nervous system ANS in depression. According to the Polyvagal Theory of the ANS, depression is part of a biological defense strategy meant to help us survive.
That biological strategy is called immobilization, and that — it was, or is believed — manifests in the mind and the body with a set of symptoms we have come to label as depression.
The problem with the old way of thinking, is that when we think of depression as irrational suffering, we stigmatize people and potentially rob them of hope, argues Escalante.
But when we change our approach and consider depression, at least initially, happens for a good reason — we begin to lift the shame that many suffer, possibly breaking the negative cycle. This will be more than familiar to the approach taken in yoga therapy. If this way of looking at depression could be adopted by society at large, we could start to see that people with depression are courageous survivors, not damaged.
The article in Psychology Today explains how, If depression is the emotional expression of the immobilization response, then the solution is to move out of that state of defense. Porges Polyvagal theory proposes that it is not enough to simply remove the threat. Rather, the nervous system has to detect robust signals of safety to bring the social state back online. And the best way to do that? Via Social connection. Alison Escalante M. When people are told that depression is an aberration, we are telling them that they are not part of the tribe.
We have cut them noff from the path that leads them out of depression. It is time that we start honoring the courage and strength of depressed people. It is time we start valuing the incredible capacity of our biology to find a way in hard times. Your email address will not be published.
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